Joseph Edelman – Perceptive Advisors LLC

Period:
Q1 2026
Portfolio date:
Mar 31, 2026
No. of stocks:
91
Portfolio value:
$5,110,912,000
Filed:
May 15, 2026
Style:
Biotech Specialist
HistStockActivityShare change% change to portfolio
Q1 2026filed May 15, 2620 new17 added22 reduced42 exited
≡CNTA – CENTESSA PHARMACEUTICALS PLCAdd 80.00%2,341,2692.79
≡ASND – ASCENDIS PHARMA A/SAdd 42.00%450,0002.74
≡SYRE – SPYRE THERAPEUTICS INCAdd 23.00%714,0001.94
≡RLAY – RELAY THERAPEUTICS INCAdd 412.00%7,847,8961.61
≡MRNAPUT – MODERNA INCBuy1,000,0000.99
≡BCRX – BIOCRYST PHARMACEUTICALS INCAdd 135.00%4,271,5040.95
≡IONS – IONIS PHARMACEUTICALS INCBuy504,0000.74
≡DAWN – DAY ONE BIOPHARMACEUTICALS IBuy1,755,7990.74
≡DMRA – DAMORA THERAPEUTICS INCBuy1,223,0000.62
≡CRVS – CORVUS PHARMACEUTICALS INCAdd 231.00%1,600,0000.56
≡RVMD – REVOLUTION MEDICINES INCBuy258,6000.49
≡DYN – DYNE THERAPEUTICS INCAdd 34.00%1,189,8950.44
≡SABS – SAB BIOTHERAPEUTICS INCAdd 701.00%5,628,5330.43
≡DBVT – DBV TECHNOLOGIES S ABuy964,3910.39
≡TENX – TENAX THERAPEUTICS INCAdd 230.00%1,008,6400.36
≡STRO – SUTRO BIOPHARMA INCBuy715,3070.35
≡ANRO – ALTO NEUROSCIENCE INCAdd 13.00%225,5000.32
≡GH – GUARDANT HEALTH INCAdd 88.00%140,0000.25
≡TNGX – TANGO THERAPEUTICS INCAdd 58.00%295,1180.25
≡AVR – ANTERIS TECHNOLOGIES GLOBALAdd 104.00%1,750,0000.22
≡EVMN – EVOMMUNE INCBuy448,3500.20
≡PHAT – PHATHOM PHARMACEUTICALS INCBuy925,0000.20
≡NMRA – NEUMORA THERAPEUTICS INC.Buy5,104,0970.19
≡ZYME – ZYMEWORKS INCAdd 8.00%248,2280.19
≡BBNX – BETA BIONICS INCAdd 40.00%240,000−0.16
≡TWST – TWIST BIOSCIENCE CORPBuy150,0000.14
≡SRZN – SURROZEN INCBuy229,3930.13
≡AGMB – AGOMAB THERAPEUTICS NVBuy600,0000.12
≡EOLS – EVOLUS INCBuy1,286,8620.10
≡XFOR – X4 PHARMACEUTICALS INCAdd 7.00%423,1960.09
≡OCULCALL – OCULAR THERAPEUTIX INCBuy500,0000.08
≡APLS – APELLIS PHARMACEUTICALS INCBuy80,9560.06
≡EDSA – EDESA BIOTECH INCBuy563,2390.06
≡ADPT – ADAPTIVE BIOTECHNOLOGIES CORBuy152,5000.04
≡CORT – CORCEPT THERAPEUTICS INCBuy50,0000.04
≡BLLN – BILLIONTOONE INCAdd 26.00%19,0000.04
≡XGN – EXAGEN INCBuy114,8930.01
Q4 2025filed Feb 17, 2641 new31 added17 reduced15 exited
≡PRAX – PRAXIS PRECISION MEDICINES IAdd 28.00%431,4328.14
≡RYTM – RHYTHM PHARMACEUTICALS INCBuy2,546,3913.67
≡XBIPUT – SPDR SERIES TRUSTBuy1,100,0002.39
≡APGE – APOGEE THERAPEUTICS INCAdd 72.00%978,6621.62
≡CELC – CELCUITY INCAdd 7.00%203,8811.49
≡EXAS – EXACT SCIENCES CORPAdd 158.00%735,0001.45
≡SYRE – SPYRE THERAPEUTICS INCAdd 150.00%1,839,7801.21
≡BLTE – BELITE BIO INCAdd 732.00%364,4511.08
≡DYN – DYNE THERAPEUTICS INCAdd 544.00%2,938,5001.02
≡IVVD – INVIVYD INCBuy21,785,1660.96
≡NRIX – NURIX THERAPEUTICS INCAdd 151.00%2,139,7280.83
≡NUVL – NUVALENT INCAdd 7.00%102,769−0.83
≡DHR – DANAHER CORPORATIONBuy200,0000.82
≡BSX – BOSTON SCIENTIFIC CORPAdd 216.00%669,0000.81
≡VRDN – VIRIDIAN THERAPEUTICS INCAdd 108.00%1,580,3030.80
≡INBX – INHIBRX BIOSCIENCES INCAdd 9.00%125,0000.78
≡CDTX – CIDARA THERAPEUTICS INCBuy165,1310.65
≡IRON – DISC MEDICINE INCBuy450,7430.64
≡ANRO – ALTO NEUROSCIENCE INCAdd 1049.00%1,629,0270.55
≡ENGN – ENGENE HOLDINGS INCAdd 180.00%3,771,8400.54
≡ZYME – ZYMEWORKS INCAdd 56.00%1,171,1870.52
≡JAZZ – JAZZ PHARMACEUTICALS PLCBuy170,0000.52
≡PALI – PALISADE BIO INCBuy12,050,0000.50
≡AXGN – AXOGEN INCBuy784,1400.46
≡XFOR – X4 PHARMACEUTICALS INCBuy6,314,4520.45
≡BCRX – BIOCRYST PHARMACEUTICALS INCBuy3,162,5290.44
≡BIIB – BIOGEN INCBuy124,0000.39
≡MIRM – MIRUM PHARMACEUTICALS INCBuy259,5450.37
≡RAPT THERAPEUTICS INCAdd 349.00%642,0000.36
≡GRAL – GRAIL INCBuy237,3420.36
≡TVTX – TRAVERE THERAPEUTICS INCAdd 13.00%483,5650.35
≡IMTX – IMMATICS N.VAdd 11.00%1,000,000−0.31
≡CVS – CVS HEALTH CORPBuy220,0000.31
≡GH – GUARDANT HEALTH INCBuy160,0000.29
≡RLAY – RELAY THERAPEUTICS INCBuy1,903,2450.29
≡GKOS – GLAUKOS CORPBuy140,0000.28
≡DXCM – DEXCOM INCBuy225,7580.27
≡SVRA – SAVARA INCBuy2,400,0000.26
≡EWTX – EDGEWISE THERAPEUTICSAdd 17.00%662,0800.23
≡INTU – INTUITIVE SURGICAL INCAdd 69.00%35,8000.23
≡LONA – ATHIRA PHARMA INCAdd 244.00%1,319,0260.19
≡IMVT – IMMUNOVANT INCAdd 26.00%407,0000.18
≡OCS – OCULIS HOLDING AGBuy493,8270.18
≡MPLT – MAPLIGHT THERAPEUTICS INCBuy550,0000.17
≡BBNX – BETA BIONICS INCAdd 117.00%325,0000.17
≡ABVX – ABIVAX SAAdd 18.00%69,7350.17
≡PTGX – PROTAGONIST THERAPEUTICS INCAdd 31.00%320,2910.17
≡KMTS – KESTRA MED TECHNOLOGIES LTDBuy285,0000.13
≡KOD – KODIAK SCIENCES INCAdd 34.00%214,3230.13
≡CAPRCALL – CAPRICOR THERAPEUTICS INCBuy242,1000.12
≡ORKA – ORUKA THERAPEUTICS INCAdd 16.00%208,4800.11
≡BLLN – BILLIONTOONE INCBuy72,8120.11
≡BHVNCALL – BIOHAVEN LTDBuy500,0000.10
≡RGEN – REPLIGEN CORPAdd 17.00%45,113−0.10
≡TENX – TENAX THERAPEUTICS INCBuy439,1420.10
≡TECXCALL – TECTONIC THERAPEUTIC INCBuy250,0000.09
≡TNGX – TANGO THERAPEUTICS INCBuy513,0350.08
≡COGT – COGENT BIOSCIENCES INCBuy121,0820.08
≡OLMA – OLEMA PHARMACEUTICALS INCBuy165,7130.07
≡SDGR – SCHRODINGER INCBuy202,4000.06
≡CTNM – CONTINEUM THERAPEUTICS INCAdd 105.00%750,0000.06
≡ROIV – ROIVANT SCIENCES LTDAdd 8.00%617,000−0.06
≡SABS – SAB BIOTHERAPEUTICS INCBuy803,2100.05
≡CNTB – CONNECT BIOPHARMA HLDGS LTDBuy792,6960.04
≡IMMX – IMMIX BIOPHARMA INCBuy338,9410.03
≡RAPP – RAPPORT THERAPEUTICS INCAdd 67.00%270,0000.03
≡CPIX – CUMBERLAND PHARMACEUTICALS IBuy341,0870.02
≡MDLN – MEDLINE INCBuy28,0000.02
≡PTN – PALATIN TECHNOLOGIES INCBuy70,0000.02
≡LENZ – LENZ THERAPEUTICS INCBuy50,0000.01
≡IOVA – IOVANCE BIOTHERAPEUTICS INCBuy152,7140.01
≡CELC – CELCUITY INCBuy6,500,0000.00
Q3 2025filed Nov 14, 2521 new28 added14 reduced13 exited
≡CELC – CELCUITY INCAdd 81.00%1,323,1113.34
≡MERUS N VAdd 91.00%644,9172.25
≡TVTX – TRAVERE THERAPEUTICS INCAdd 355.00%2,960,3632.11
≡ROIV – ROIVANT SCIENCES LTDAdd 121.00%4,036,9961.79
≡AMLX – AMYLYX PHARMACEUTICALS INCAdd 13.00%1,050,0001.60
≡CNTA – CENTESSA PHARMACEUTICALS PLCAdd 170.00%1,953,9671.58
≡PEN – PENUMBRA INCAdd 572.00%187,7501.27
≡PRAX – PRAXIS PRECISION MEDICINES IAdd 108.00%811,6331.20
≡ABVX – ABIVAX SABuy388,6080.93
≡INBX – INHIBRX BIOSCIENCES INCAdd 36.00%349,8150.76
≡EXAS – EXACT SCIENCES CORPBuy465,4870.72
≡PVLA – PALVELLA THERAPEUTICS INC NEBuy395,0930.70
≡ORKA – ORUKA THERAPEUTICS INCBuy1,268,0210.69
≡VRDN – VIRIDIAN THERAPEUTICS INCAdd 227.00%1,014,8930.67
≡NBIX – NEUROCRINE BIOSCIENCES INCAdd 76.00%195,0000.63
≡IRTC – IRHYTHM TECHNOLOGIES INCBuy123,0000.60
≡INSM – INSMED INCAdd 8.00%51,8780.49
≡ZYME – ZYMEWORKS INCAdd 64.00%815,3890.43
≡ENGN – ENGENE HOLDINGS INCBuy2,097,2360.40
≡DRUG – BRIGHT MINDS BIOSCIENCES INCAdd 7.00%28,6000.37
≡APGE – APOGEE THERAPEUTICS INCAdd 14.00%169,841−0.34
≡RAPP – RAPPORT THERAPEUTICS INCBuy403,9230.34
≡AQST – AQUESTIVE THERAPEUTICS INCAdd 72.00%1,569,6790.33
≡CTMX – CYTOMX THERAPEUTICS INCAdd 38.00%2,686,5390.30
≡KOD – KODIAK SCIENCES INCBuy634,5770.29
≡GOSS – GOSSAMER BIO INCBuy3,812,7970.28
≡RGEN – REPLIGEN CORPAdd 63.00%104,4280.27
≡CELC – CELCUITY INCBuy00.25
≡AKERO THERAPEUTICS INCAdd 24.00%219,879−0.24
≡BSX – BOSTON SCIENTIFIC CORPAdd 11.00%30,000−0.23
≡ISRG – INTUITIVE SURGICAL INCAdd 16.00%7,000−0.23
≡ALDX – ALDEYRA THERAPEUTICS INCAdd 29.00%1,170,6800.21
≡TEM – TEMPUS AI INCBuy85,0000.19
≡KRYS – KRYSTAL BIOTECH INCBuy35,0000.17
≡HTFL – HEARTFLOW INCBuy150,0000.14
≡NVNO – ENVVENO MEDICAL CORPORATIONAdd 37.00%474,069−0.14
≡PEPG – PEPGEN INCBuy829,8700.11
≡BLTE – BELITE BIO INCBuy49,7880.10
≡ASND – ASCENDIS PHARMA A/SAdd 13.00%124,6150.10
≡NRIX – NURIX THERAPEUTICS INCAdd 29.00%319,164−0.08
≡OBIO – ORCHESTRA BIOMED HLDGS INCAdd 15.00%700,000−0.07
≡PYXS – PYXIS ONCOLOGY INCBuy1,178,3070.07
≡LONA – ATHIRA PHARMA INCBuy540,2960.06
≡SPRYPUT – ARS PHARMACEUTICALS INCBuy200,0000.06
≡QURE – UNIQURE NVBuy20,0000.03
≡SCPHARMACEUTICALS INCAdd 17.00%83,1420.02
≡BDSX – BIODESIXBuy108,6940.02
≡NUVL – NUVALENT INCAdd 14.00%187,1560.02
≡ANRO – ALTO NEUROSCIENCE INCBuy155,3660.02
Q2 2025filed Aug 14, 2522 new8 added27 reduced23 exited
≡ASND – ASCENDIS PHARMA A/SBuy963,8866.01
≡EWTX – EDGEWISE THERAPEUTICS INCAdd 828.00%4,139,9491.81
≡OMDA – OMADA HEALTH INCBuy2,426,3301.61
≡ROIV – ROIVANT SCIENCES LTDBuy3,331,4651.36
≡CAI – CARIS LIFE SCIENCES INCBuy1,098,1631.06
≡INSM – INSMED INCAdd 28.00%140,9521.00
≡XBIPUT – SPDR SERIES TRUSTBuy300,0000.90
≡NBIX – NEUROCRINE BIOSCIENCES INCAdd 155.00%155,0000.77
≡AKERO THERAPEUTICS INCAdd 16.00%122,9270.64
≡BSX – BOSTON SCIENTIFIC CORPAdd 115.00%150,0000.63
≡CTMX – CYTOMX THERAPEUTICS INCBuy6,993,6460.57
≡CRL – CHARLES RIV LABS INTL INCBuy100,0000.55
≡TVTX – TRAVERE THERAPEUTICS INCBuy834,2520.45
≡RARE – ULTRAGENYX PHARMACEUTICAL INBuy270,0000.35
≡KYMR – KYMERA THERAPEUTICS INCBuy210,1060.33
≡NRIX – NURIX THERAPEUTICS INCAdd 269.00%799,4320.33
≡PEN – PENUMBRA INCBuy32,7970.30
≡CBIO – CRESCENT BIOPHARMA INC.Buy453,6860.26
≡CAPRPUT – CAPRICOR THERAPEUTICS INCBuy650,0000.23
≡CRVS – CORVUS PHARMACEUTICALS INCBuy1,438,5950.21
≡SEPN – SEPTERNA INCBuy541,4500.21
≡GMED – GLOBUS MED INCBuy88,5000.19
≡NVNO – ENVVENO MEDICAL CORPORATIONBuy1,284,9660.19
≡ISRG – INTUITIVE SURGICAL INCAdd 11.00%4,5000.18
≡RGEN – REPLIGEN CORPAdd 28.00%36,1990.17
≡LYRA – LYRA THERAPEUTICS INCBuy255,1500.08
≡RAPT THERAPEUTICS INCBuy183,8900.05
≡TRIB – TRINITY BIOTECH PLCBuy1,790,0000.04
≡CAPRCALL – CAPRICOR THERAPEUTICS INCBuy100,0000.04
≡FBRX – FORTE BIOSCIENCES INCBuy68,1920.03
Q1 2025filed May 15, 2515 new13 added29 reduced27 exited
≡EWTX – EDGEWISE THERAPEUTICS INCAdd 144.00%3,861,7913.10
≡INSM – INSMED INCAdd 254.00%365,3001.09
≡BBNX – BETA BIONICS INCBuy2,203,8400.95
≡SLDB – SOLID BIOSCIENCES INCAdd 72.00%5,000,0000.79
≡MERUS N VAdd 130.00%390,4850.68
≡RGEN – REPLIGEN CORPBuy129,8010.58
≡MDGL – MADRIGAL PHARMACEUTICALS INCBuy46,5000.54
≡ADMA – ADMA BIOLOGICS INCAdd 54.00%482,9530.54
≡DYN – DYNE THERAPEUTICS INCAdd 326.00%1,770,1260.50
≡BSX – BOSTON SCIENTIFIC CORPBuy130,0000.46
≡SION – SIONNA THERAPEUTICS INCBuy1,251,1010.46
≡DXCM – DEXCOM INCBuy178,0000.43
≡AQST – AQUESTIVE THERAPEUTICS INCBuy3,727,2080.38
≡OM – OUTSET MED INCBuy833,3330.32
≡AMLX – AMYLYX PHARMACEUTICALS INCAdd 16.00%1,100,0000.28
≡JANX – JANUX THERAPEUTICS INCAdd 19.00%152,517−0.27
≡IMVT – IMMUNOVANT INCAdd 33.00%704,8730.26
≡IRON – DISC MEDICINE INCBuy150,0000.26
≡ADPT – ADAPTIVE BIOTECHNOLOGIES CORBuy930,9720.24
≡DCTH – DELCATH SYS INCAdd 825.00%412,4220.19
≡APGE – APOGEE THERAPEUTICS INCAdd 7.00%75,5350.18
≡KMTS – KESTRA MED TECHNOLOGIES LTDBuy200,0000.17
≡DRUG – BRIGHT MINDS BIOSCIENCES INCAdd 10.00%41,0000.17
≡IRD – OPUS GENETICS INCBuy4,325,0000.15
≡AVTX – AVALO THERAPEUTICS INCBuy520,0000.15
≡KALA – KALA BIO INCBuy277,6100.06
≡CGEM – CULLINAN THERAPEUTICS INCBuy80,1000.02
≡TRAW – TRAWS PHARMA INCAdd 157.00%257,624−0.01